As many readers of this blog will know, I have 癌. I’ve had many 操作／手術s over the last fifteen years, but a few years ago we decided that the spread was now wide enough that その上の 外科 was not very pointful; we should instead wait for particular lesions to start 原因（となる）ing problems, and only then 扱う／治療する them. (I have metastases in my 肺s, 肝臓, remaining 腎臓, 脚, pleura and other places.)
歴史的に, chemotherapy hasn’t been an 選択 for me. 幅の広い spectrum chemotherapies work by 殺人，大当り anything growing 急速な／放蕩な; but my rather unusual 癌 doesn’t grow 急速な／放蕩な (which is why I’ve lived as long as I have so far) and so they would kill me as quickly as they would kill it. And there are no targetted 麻薬s for Adenoid Cystic Carcinoma, the rare salivary （分泌する為の）腺 癌 I have.
However, recently my oncologist referred me to The Christie hospital in Manchester, which is doing some 利益／興味ing 研究 on 癌 genetics. With them, I’m trying a few things, but the most 即座の is that yesterday I entered a 段階 1 裁判，公判 called AToM, which is trialling a couple of 麻薬s in combination which may be able to help me.
The two 麻薬s are an 存在するing 麻薬 called olaparib, and a new one known only as AZD0156. Each of these 麻薬s inhibits a different one of the seven or so 機械装置s 独房s use to 修理 デオキシリボ核酸 after it’s been 損失d. (Olaparib inhibits the PARP pathway; AZD0156 the ATM pathway.) 独房s which realise they can’t 修理 themselves commit “独房 自殺” (apoptosis). The theory is that these 修理 機械装置s are shakier in 癌 独房s than normal 独房s, and so 癌 独房s should be 不均衡な 影響する／感情d (and so commit 自殺 more) if the 機械装置s are inhibited.
As this is a 段階 1 裁判，公判, the goal is more about making sure the 麻薬 doesn’t kill people than about whether it 作品 井戸／弁護士席, although the doses now 存在 used are in the 臨床の 範囲, and another 患者 with my 癌 has seen some 改良. The 裁判，公判 文書 名簿（に載せる）／表（にあげる）d all sorts of possible 味方する-影響s, but the doctors say other 患者s are 許容するing the combination 井戸／弁護士席. Only experience will tell how it 影響する／感情s me. I’ll be on the 麻薬s as long as I am seeing 利益 (defined as “my 癌 is not growing”). And, of course, hopefully there will be 利益 to people in the 未来 when and if this 麻薬 is 認可するd for use.
In practical 条件, the first three weeks of the 裁判，公判 are やめる 集中的な ーに関して／ーの点でs of the 量 of hospital visits 要求するd (and I live 2 hours 運動 from Manchester), and the に引き続いて six weeks moderately 集中的な, so I may be いっそう少なく responsive to email than normal. I also won’t be doing any international travel.
Wishing you the best possible luck for this 裁判，公判 段階. I 信用 your mental strength to 耐える it!
Thank you for 地位，任命するing these 詳細（に述べる）s; 利益／興味ing stuff.
I will keep you in my 祈りs.
Gervase I have 静かに followed you for many a year.
Thank you for 存在 so upfront. You are in our 祈りs
Best wishes, Gerv. Keep fighting!